Winger Darcy Graham was the star of the show as he scored four tries.
Hamish Watson, Ali Price, Matt Fagerson, Chris Harris, Ollie Smith, Johnny Matthews, Rory Darge and Ben Healy also scored tries, as the latter matched Chris Paterson’s Scotland record of 11 conversions set in a Test against Japan in 2004.
Scotland move on to 10 points in the pool, level with South Africa, who play their final group game against Tonga in Marseille on Sunday.
Ireland lead with 14 points and all three teams are in contention for the two quarter-final places available.
Romania, porous in defence throughout the tournament having conceded 242 points in three games, were kept scoreless for the second match in a row.
They were not helped by three yellow cards in a 10-minute spell before halftime.
